The Basilica of San Sebastiano fuori le Mura sits on the Ancient Appian Way, Rome's major north-south road. Saint Sebastian, an early martyr, was killed by being tied to a tree and shot with arrows, a popular image in art. This church, one of Rome's oldest, was established under Constantine but heavily renovated. Its location near the catacombs and Appian Way makes it a worthwhile stop outside the city.